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Mesc Hole?
| Good [+1]Toggle ReplyLink» ashtraygirl replied on Tue Feb 10, 2004 @ 3:15am |
 Coolness: 89485 | i read every word |
| Good [+1]Toggle ReplyLink» beercrack replied on Wed Jul 7, 2004 @ 11:50am |
 Coolness: 71435 | just trolling ;)
Originally posted by [SCREWHEAD]...
You mean this part? the one that says that it shares a similar carbon skeleton but NONE of the features of actual amphetamines? Yeah, that's the one, I'll bet. A final comment is in order concerning the frequent use of the term "amphetamines" to describe these compounds. With the exception of some of the peyote components, all of the centrally active substances that have been discussed here contain the carbon skeleton of the amphetamine molecule. Yet almost none of them display the sympathomimetic stimulation that is the reputation of am- phetamine. The popular use of the term "amphetamines" has come to embrace a large number of currently used drugs that are stimulants, and which call upon these effects for their effectiveness. Examples of this are amphetamine itself (and its dextrorotatory isomer, dexedrine), methamphetamine, methylphenidate (Ritalin), phenmetrazine (Preludin) and mephenteramine (Wyamine). An excellent demonstration of the separation of these pharmacological areas may be se,., from the fact that the active isomer of DOM (35) is the R (-) form. The S (+) form shows only stimulant properties, and this is the same absolute configuration as that seen in the stimulatively active isomer of amphetamine itself, S-(+) -dextroamphetamine (52). you nerdsnot here it says Peyote (Lophophora Williamsii) is a spineless cactus with a long root. It grows in the southwesterm United States and Mexico. Its crown, or 'button', is used for psychedelic purposes. It is cut from the cactus and dried into a hard brown disc. The disc, sometimes referred to as a 'mescal button', contains a methoxylated amphetamine: mescaline (C11H17NO3) (3,4,5-trimethoxy-ß-phenethylamine). The primary natural sources of mescaline are peyote (Lophophora williamsii or Lophophora diffusa); San Pedro cactus (Trichocereus pachanoi); and Peruvian Torch (Trichocereus peruvianus) Mescaline is one of a large group of psychedelic drugs which are structurally similar to the catecholamine neurotransmitters, dopamine and noradrenaline (norepinephrine). The addition of one or more methoxy (OCH3) groups to the carboxy ring structure confers psychedelic properties. Other methoxylated amphetamine derivatives include MDMA (ecstasy), MDA, MMDA, DOM (STP), TMA and DMA. Despite their catecholamine-like actions on the body, the psychedelic properties of these drugs at higher doses is mediated mainly by their effect on the neurotransmitter serotonin, particularly via the 5HT2a serotonin receptor. so not only is mescaline a methoxylated amphetamine. but all you Ecstacy freaks are practically praying to the pagan cactus god. :P [ mescaline.com ] |
Mesc Hole?
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